Data for the article "Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief"

Published: 15 January 2025| Version 1 | DOI: 10.17632/rmm4jtxmpp.1
Contributors:
,
,
, Nick Wright, Wei He, Justin Fedor

Description

Data for the manuscript entitled "Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief". In summary, we conducted chemical synthesis, protein 3D structure determination, in vitro radioactive binding and uptake experiments, imaging, electrophysiological studies, as well as animal behavioral and pharmacokinetic studies. We provide the data that were used in this manuscript.

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Institutions

Duke University, Duke Medicine

Categories

Biochemistry, Electrophysiology, Chemical Synthesis, Cellular Imaging

Funding

National Institute of Neurological Disorders and Stroke

R61NS138215

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