The lung commensal Lactobacillus protects against bacterial pulmonary infections by driving an interleukin-17 response from mucosal Vγ4+γδ T cells.

Published: 14 June 2024| Version 1 | DOI: 10.17632/s7c5pyy87p.1
Contributors:
Xiao Wang, Haochi Zhang, Xuemei Bao, Chunhe Li, Yanchen Liang, Na Pan, Bin Ma, Shouxin Sheng, Jian Chen, Pingyuan Guan, Yubing Fu

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Original data of this manuscript.

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16S Ribosomal DNA Gene Sequencing, Transcriptomics analysis, ELISA, Flow cytometric and other methods were used in this study.All experiments were performed in triplicate. GraphPad software program was used for data processing and analysis. Significance of differences with p< 0.05 was determined by analysis of variance (ANOVA). Differences among three or more groups were analyzed by one- or two-way ANOVA multiple comparisons. Significance of differences was classified as *p< 0.05, **p< 0.01, ***p< 0.001, or n.s. (not significant).

Categories

Life Sciences, Microbiota

Funders

  • Science and Technology Major Project of the Inner Mongolia Autonomous Region of China
    Grant ID: 2021ZD0013
  • Key Scientific and Technological Research Program of Inner Mongolia Autonomous Region
    Grant ID: 2021GG0156
  • Technology Major Project of Hohhot
    Grant ID: 2023-JieBangGuaShuai
  • China Postdoctoral Science Foundation
    China
    Grant ID: 2023MD734180

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https://doi.org/10.7910/DVN/D85KBA
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