Base editing of the HBG promoter induced potent  fetal hemoglobin with no detectable off-target  mutations in human HSCs

Name: Base editing of the HBG promoter induced potent fetal hemoglobin with no detectable off-target mutations in human HSCs
Creator: ying zhang
Published: 2023-10-11T15:50:46.068Z
Keywords: Hematopoietic Stem Cell Transplantation, Beta Thalassemia

zhang, ying; Qiu, Houyuan

doi:10.17632/sf7zywbswy.4

Base editing of the HBG promoter induced potent fetal hemoglobin with no detectable off-target mutations in human HSCs

Published: 11 October 2023| Version 4 | DOI: 10.17632/sf7zywbswy.4

Contributors:

ying zhang, Houyuan Qiu

Description

raw FACS data of fetal hemoglobin expression in HSPCs and bone marrow transplantation experiments in NBSGW mice

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Wuhan University

Base editing of the HBG promoter induced potent fetal hemoglobin with no detectable off-target mutations in human HSCs

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