Mendeley Supplemental Material
Description
This dataset includes supplemental methods, supplemental tables 1-6, and supplemental figures 1-7 for the original article: Development of Gene-Expression Panel Predictive of Local Recurrence, Metastasis, and Overall Survival in Intermediate to High-risk Cutaneous Squamous Cell Carcinoma: A Cohort Study in the Journal of the American Academy of Dermatology. The SupplementalMaterial.docx file contains all supplemental materials. The RNA Nanostring data are available in supplemental table 1 and can be accessed through the TableS1.xlsx file. Mendeley Supplemental Table 1. Differentially expressed genes in 186 samples. Mendeley Supplemental Table 2. Risk score comparison between metastasis and non-metastasis groups. Mendeley Supplemental Table 3. Risk score comparison between local recurrence and non-local recurrence groups. Mendeley Supplemental Table 4. Risk score by BWH tumor stage. Mendeley Supplemental Table 5. Metastasis by Metastasis risk score with BWH staging. Mendeley Supplemental Table 6. Multivariable Cox regression model summary for overall survival. Mendeley Supplemental Figure 1. Gene panel data using Nanostring platform. Mendeley Supplemental Figure 2. Volcano plot with all modeling-selected genes highlighted. Mendeley Supplemental Figure 3. Model-predicted genes associated with Metastasis. Mendeley Supplemental Figure 4. Receiver operating characteristic curve (ROC) for the risk score to predict local recurrence. Mendeley Supplemental Figure 5. Overall Survival by Risk Groups with BWH staging. Mendeley Supplemental Figure 6. Overall survival KM curves by risk scores (CXCL8, ZNF750, CDCA5, KRT2, ALOX12, ALDH3A2, DMD) in 3 groups (risk scores by (0,1), (2,3,4), (5,6)). Mendeley Supplemental Figure 7. Heat map presenting calculated Pearson correlation coefficients using the genes’ normalized raw expression data.
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Institutions
- Mayo Clinic Arizona
- Mayo Clinic Minnesota
- Complejo Asistencial Universitario de Salamanca
- Instituto de Investigacion Biomedica de Salamanca
- Instituto de Biologia Molecular y Celular del Cancer