TLR4 in Breast Cancer
Published: 11 December 2024| Version 1 | DOI: 10.17632/ss5vgk8f7z.1
Contributors:
Wassim Almawi, Description
Breast cancer (BC) is heterogeneous in clinical manifestation, of which the triple negative (TNBC) subtype is the most aggressive. This study examines the associations between Toll-Like Receptor (TLR)-4 polymorphisms and the susceptibility to BC and TNBC. Genotyping of TLR-4 rs2770150, rs2149356, rs1554973 and rs7856729 polymorphisms was done by real-time PCR in 488 women with BC (130 TNBC, 358 non-TNBC), and 476 cancer-free control women.
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Institutions
Universite de Monastir
Categories
Breast Cancer, Triple-Negative Breast Cancer