TLR4 in Breast Cancer

Published: 11 December 2024| Version 1 | DOI: 10.17632/ss5vgk8f7z.1
Contributors:
Wassim Almawi, Rabeb Ghali

Description

Breast cancer (BC) is heterogeneous in clinical manifestation, of which the triple negative (TNBC) subtype is the most aggressive. This study examines the associations between Toll-Like Receptor (TLR)-4 polymorphisms and the susceptibility to BC and TNBC. Genotyping of TLR-4 rs2770150, rs2149356, rs1554973 and rs7856729 polymorphisms was done by real-time PCR in 488 women with BC (130 TNBC, 358 non-TNBC), and 476 cancer-free control women.

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Institutions

  • Universite de Monastir

Categories

Breast Cancer, Triple-Negative Breast Cancer

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