Data for: Distribution of connective tissue in the male and female porcine liver: Histological mapping and recommendations for sampling of tissue probes

Published: 28 Jun 2018 | Version 1 | DOI: 10.17632/ssgd4mwgsj.1
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Description of this data

Supplement 1. Primary stereological data on volume fraction of connective tissue and cross-sectional area of classical lobules in all investigated samples. The following abbreviations are used: VV(ICT) – volume fraction of interlobular connective tissue (connective tissue surrounding liver lobule), VV(PSCT) – volume fraction of perisinusoidal connective tissue (connective tissue located at the lobular sinusoids), VV(PCCT) – volume fraction of pericentral connective tissue (connective tissue surrounding central vein), VV(CT) – volume fraction of total connective tissue (sum of all connective tissue volume fractions).

Supplement 2. Calculating sample sizes needed to detect a certain expected relative increase in the connective tissue fraction in various hepatic lobes. VV(CT) – volume fraction of connective tissue (total connective tissue irrespective of its localization), n – number of tissue blocks in each of the groups that are to be compared. Sample sizes were calculated according to Chow et al. (power=0.8; significance level=0.05) (2008). The data are presented for both sexes.

Supplement 3. Calculating sample size needed to detect a certain expected relative increase in the connective tissue fraction in various regions of interests (ROIs) within hepatic lobes. Peripheral ROI – region at the periphery of a liver lobe, paraportal ROI – region of a lobe near the porta hepatis, paracaval ROI – region of a lobe adjacent to the caudal vena cava, VV(CT) – volume fraction of connective tissue (total connective tissue irrespective of its localization), n – number of tissue blocks in each of the compared groups. Sample size were calculated according to Chow et al. (power=0.8; significance level=0.05) (2008). The data are presented for both sexes and each ROI within each hepatic lobe.

Experiment data files

This data is associated with the following publication:

Distribution of Connective Tissue in the Male and Female Porcine Liver: Histological Mapping and Recommendations for Sampling

Published in: Journal of Comparative Pathology

Latest version

  • Version 1

    2018-06-28

    Published: 2018-06-28

    DOI: 10.17632/ssgd4mwgsj.1

    Cite this dataset

    Tonar, Zbynek; Palek, Richard; Eberlova, Lada; Kralickova, Milena; Mik, Patrik; Witter, Kirsti; Jirik, Miroslav; Mírka, Hynek; Maleckova, Anna; Liska, Vaclav (2018), “Data for: Distribution of connective tissue in the male and female porcine liver: Histological mapping and recommendations for sampling of tissue probes”, Mendeley Data, v1 http://dx.doi.org/10.17632/ssgd4mwgsj.1

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Categories

Liver, Fibrosis, Stereology, Sampling, Animal Histology

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