COMPARATIVE STUDY OF RELATION OF D-DIMER LEVELS OF COVID-19 PATIENTS WITH DIABETES MELLITUS
Description
Coronavirus is enveloped positive-sense, single-stranded RNA viruses belonging to the Coronaviridae family. Diabetes has been identified as a strong predictor of disease severity in COVID-19. Healthy individuals have low levels of circulating D-dimer, whereas elevated levels are found in conditions associated with hypercoagulation and increased fibrinolytic activity. This study aims to study D-dimer levels in people with diabetes compared to those without diabetes among patients with COVID-19. Marked elevation in D-dimer levels in patients with diabetes compared to non-diabetes. D-dimer may be considered a reliable parameter for evaluating the prognosis and predicting mortality.
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Steps to reproduce
The present study is a prospective cohort study, and the calculated sample size was 60. Covid 19 was confirmed by RT-PCR (Real Time Reverse Transcription Polymerase Chain Reaction) or RAT (Rapid Antigen Test). Patients with a history of diabetes and with Hba1c>6.5 were considered. Comparisons among different groups were performed using the ANOVA test, and significant differences among pairs of means were tested using Scheffe’s test.
Institutions
- Rajasthan University of Health Sciences
- SMS Medical College and Hospital