COMPARATIVE STUDY OF RELATION OF D-DIMER LEVELS OF COVID-19 PATIENTS WITH DIABETES MELLITUS

Published: 21 April 2023| Version 1 | DOI: 10.17632/sstdyv2kdy.1
Contributors:
S S Dariya, I Harshvardhan, M Dinesh,

Description

Coronavirus is enveloped positive-sense, single-stranded RNA viruses belonging to the Coronaviridae family. Diabetes has been identified as a strong predictor of disease severity in COVID-19. Healthy individuals have low levels of circulating D-dimer, whereas elevated levels are found in conditions associated with hypercoagulation and increased fibrinolytic activity. This study aims to study D-dimer levels in people with diabetes compared to those without diabetes among patients with COVID-19. Marked elevation in D-dimer levels in patients with diabetes compared to non-diabetes. D-dimer may be considered a reliable parameter for evaluating the prognosis and predicting mortality.

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The present study is a prospective cohort study, and the calculated sample size was 60. Covid 19 was confirmed by RT-PCR (Real Time Reverse Transcription Polymerase Chain Reaction) or RAT (Rapid Antigen Test). Patients with a history of diabetes and with Hba1c>6.5 were considered. Comparisons among different groups were performed using the ANOVA test, and significant differences among pairs of means were tested using Scheffe’s test.

Institutions

Rajasthan University of Health Sciences, SMS Medical College and Hospital

Categories

Type 2 Diabetes, COVID-19 Diagnostics

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