Dataset on Graft-versus-Host Disease Prevalence and Risk Factors in International Stem Cell Transplant Patients from the UAE (2019-2022)
Description
This dataset comprises detailed clinical and demographic information on 91 stem cell transplant (SCT) recipients who were treated abroad and subsequently followed at a medical center in the UAE from January 2019 to December 2022. The dataset focuses on the prevalence and risk factors of graft-versus-host disease (GVHD) among these patients, with specific attention to various factors that could influence GVHD outcomes. Columns: R_Sex: Sex of the recipient Age: Age of the recipient Adult Category: Classification of the recipient as adult or pediatric Nationality: Nationality of the recipient Hematological Diagnosis: Specific hematological condition diagnosed Number of Lines of Rx Before BMT: Number of treatment lines received before BMT Indication for BMT: Reason for undergoing BMT Diagnosis to BMT Time (months): Time duration from diagnosis to BMT in months R_Age at BMT: Age of the recipient at the time of BMT R_Blood Group: Blood group of the recipient HLA Match: Human Leukocyte Antigen (HLA) match status NEW HLA: New HLA match details D_Relation: Relation of the donor to the recipient D_Sex: Sex of the donor GVHD Prophylaxis: GVHD prophylaxis measures taken GVHD: Presence of GVHD (Yes/No) GVHD Acute/Chronic: Classification of GVHD as acute or chronic GVHD Severity: Severity of GVHD (mild, moderate, severe) Skin cGVHD: Presence of chronic GVHD in the skin Liver cGVHD: Presence of chronic GVHD in the liver GI cGVHD: Presence of chronic GVHD in the gastrointestinal tract Eye cGVHD: Presence of chronic GVHD in the eyes Lung cGVHD: Presence of chronic GVHD in the lungs Dead (Y/N): Survival status of the recipient (Yes/No) Usage: This dataset can be used to analyze the prevalence and severity of GVHD in international SCT patients, understand the impact of various pre-transplant and donor-related factors on GVHD outcomes, and identify potential areas for further research. It serves as a pilot study and is the first dataset from the UAE to report on stem cell transplantation and GVHD.
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PLANNED AND PREPARED STUDY PROTOCOL ATTAINED IRB APPROVAL AT SSMC EXTRACTED PATIENT LIST FROM EMR USING SEARCH TERMS STEM CELL TRANSPLANT, BONE MARROW TRANSPLANT, GRAFT VERSUS HOST DISEASE, TRANSPLANT, SCREENED ALL PATIENTS AND SELECTED PATIENTS UNDERWENT BMT/SCT PHYSICIANS AND RESEARCHERS EXPERTISE IN HEMATOLOGY -EXTRACTED EACH DETAIL FROM EMR -INCLUDING MEDICAL REPORTS FROM TRANSPLANT CENTERS