PHARMIP

Published: 2 Dec 2019 | Version 1 | DOI: 10.17632/t26pp5y6ym.1
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Description of this data

1-Files that resulted from application of PHARMIP insilico method to explore adverse drug reactions on 2 examples of domperidone related cardio-toxicity and ranitidine related thrombocytopenia .
2-Files that are used to apply the step of molecular docking on the previous examples.

Experiment data files

Steps to reproduce

1- Use drug SMILES code to predict targets via SwissTargetPrediction, SEA server, Poly Pharmacology browser.
2- Use drug SDF file to predict targets using PharMapper.
3- Get and refine the whole off-label targets list (OLT).
4- Use the OLT list to retrieve the diseases associated (DA) to the list via DisGeNet.
5- Filter the DA list with the disease of interest.

Related links

Latest version

  • Version 1

    2019-12-02

    Published: 2019-12-02

    DOI: 10.17632/t26pp5y6ym.1

    Cite this dataset

    Zidan, Ahmad; Saad, Eman; Ibrahim, Nasser; Mahmoud, Amal ; Hashim, Medhat; Hemeida, Alaa (2019), “PHARMIP ”, Mendeley Data, v1 http://dx.doi.org/10.17632/t26pp5y6ym.1

Statistics

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Downloads: 45

Institutions

University of Sadat City

Categories

Bioinformatics, Pharmacogenetics, Pharmacovigilance

Licence

CC BY 4.0 Learn more

The files associated with this dataset are licensed under a Creative Commons Attribution 4.0 International licence.

What does this mean?
You can share, copy and modify this dataset so long as you give appropriate credit, provide a link to the CC BY license, and indicate if changes were made, but you may not do so in a way that suggests the rights holder has endorsed you or your use of the dataset. Note that further permission may be required for any content within the dataset that is identified as belonging to a third party.

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