SLC35E2B deficiency drives MAPK pathway remodeling and keratinocyte dysregulation in psoriasis-original data
Description
This repository contains the source data underlying the figures and supplementary figures of the manuscript entitled “SLC35E2B deficiency drives MAPK pathway remodeling and keratinocyte dysregulation in psoriasis.” The dataset includes original numerical data, uncropped Western blot images, quantitative real-time PCR results, immunohistochemical and immunofluorescence images, functional assay data, RNA sequencing-related files, and statistical source data generated during the study. These data support the conclusions that SLC35E2B is downregulated in psoriasis and functions as a regulator of keratinocyte homeostasis through modulation of MAPK signaling. The deposited files are provided in their original formats to enhance data transparency and reproducibility.