Osteopontin-4 (OPN-4) suppresses tumor progression features whilst sensitizing c643 anaplastic thyroid cells to sorafenib

Published: 27 January 2026| Version 1 | DOI: 10.17632/tw3rx4wcnn.1
Contributors:
, Amanda Rubim,
,
,
,

Description

This processed dataset is associated with the study “Osteopontin-4 (OPN-4) suppresses tumor progression features whilst sensitizing c643 anaplastic thyroid cells to sorafenib.” The dataset includes results from cell proliferation, viability and migration assays, cell death and cell cycle analyses, as well as experiments performed in 3D culture conditions combined with a microfluidic device. Additionally, the dataset contains data regarding the cellular response to sorafenib treatment in the context of OPN-4 expression modulation in the c643 cell line. All experiments were conducted in duplicate or triplicate, with at least three independent biological replicates. The Excel file is organized into sheets identified according to the corresponding figures presented in the article, providing essential experimental information to support data interpretation and reuse.

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Oncology, Thyroid Cancer, Cancer Research

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