Untargeted global metabolomic profiling across the 24-hour day in mouse liver under three different feeding paradigms: Nighttime feeding, Arrhythmic feeding and Arrhythmic feeding with AZD8055 administration at night

Published: 18 May 2026| Version 2 | DOI: 10.17632/v2925wd559.2
Contributors:
Aishwarya Sahasrabudhe, Jerome Menet

Description

Untargeted global metabolomic profiling from mouse liver across the 24-hour day. Liver samples were collected at 6 time points (ZT 2, 6, 10, 14, 18, 22) 4 hours apart; after different feeding paradigms or treatment conditions. The 3 groups were- night-restricted feeding (NF), arrhythmic feeding (AF) and arrhythmic feeding with AZD8055 injection (AF_AZDnight) administered at the beginning of night (ZT 11.5). Each group includes 3 replicates per time point (n=18/group) and each replicate is a mixture of two liver sample replicates.

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Categories

Mouse, Azd 8055, Metabolomics, Circadian Rhythm, Mammalian Target of Rapamycin, Liver, Metabolism, Feeding Pattern

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