The Greek version of the Oldenburg Burnout Inventory, used to assess exhaustion and disengagement from work, was analyzed using IRT analyses, to investigate the dimensionality and the psychometric properties of the measure’s items. The OLBI was administered to 617 Greek employees, from which 314 participated to the validation study (not available in this repository). Results indicated that four negatively-keyed items from the original measure exhibited excellent psychometric properties (item/test information functions) and were used for the screening version of the OLBI. The scr-OLBI was tested for differential item functioning (DIF) between male and female employees; no bias detected in relation to gender. Our results reveal that the scr-OLBI is a reliable and valid indicator of work-related burnout, which appears to be functionally equivalent to the original version both theoretically and empirically, yet pertains the advantages of a screening tool.