When Secondary Syphilis Is Reliably Recognizable

Published: 29 May 2026| Version 1 | DOI: 10.17632/v6z9g4dkgz.1
Contributors:
, Jason Lee

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Supplemental Figure 1. Oral condyloma lata presenting as bright erythematous eroded plaque (arrow) on the posterior hard palate (Case 6). Supplemental Figure 2. Fragmented specimen of oral condyloma lata that consists of bulbous and irregularly outlined pseudoepitheliomatous hyperplasia, 40x magnification. Supplemental Figure 3. Eroded area with numerous neutrophils on the surface and within the epithelium. The pseudoepitheliomatous hyperplasia consists of larger ballooned cells with abundant pink cytoplasm, along with more hyperchromatic cells with scant cytoplasm near the basal layer, 200x magnification. Supplemental Figure 4. Syphilis spirochete stain showing numerous organisms, majority situated in the lower third portion of the epithelium, 200x magnification

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