Cardiomyocyte transcriptome remodeling in response to Trypanosoma cruzi infection

Description

HL-1 rodent cardiomyocytes were infected with T. cruzi trypomastigotes of the Colombian, Y or Tulahuen strain. RNA was serially isolated post-infection for microarray analysis. Genes with signals above the threshold of 43, 48, 43, 52 at 24 and 48 hours on the T cruzi-infected (CCM model) and control conditions, respectively, were excluded leaving 11,041 and 11,000 valid gene probes for analysis. "24h_48h_ValidGenes_q_Values.xlsx" file was added containing the P-values adjusted by multiple comparisons (q-values).

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Funders

• Japan Agency for Medical Research and Development

  Japan

  Grant ID: JP21jm0110016
• Japan Agency for Medical Research and Development

  Japan

  Grant ID: JP21wm0325049
• Japan Society for the Promotion of Science

  Japan

  Grant ID: 19K23992

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