Central memory T-cells with largely unchanged TCR repertoires and gene expression profiles dominate influenza-specific CD8+ pools across human lifespan

Name: Central memory T-cells with largely unchanged TCR repertoires and gene expression profiles dominate influenza-specific CD8+ pools across human lifespan
Creator: Tejas Menon
Published: 2025-07-04T15:32:14.335Z
Keywords: Immunology, Influenza, Aging, T Cell, Cytotoxic T-Cell, Memory T Cell, T Cell Receptor

Menon, Tejas

doi:10.17632/vmxby5r95w.1

Central memory T-cells with largely unchanged TCR repertoires and gene expression profiles dominate influenza-specific CD8+ pools across human lifespan

Published: 4 July 2025| Version 1 | DOI: 10.17632/vmxby5r95w.1

Contributor:

Tejas Menon

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The files in this data repository contain the T cell receptor sequences described in the following study: Central memory T-cells with largely unchanged TCR repertoires and gene expression profiles dominate influenza-specific CD8+ pools across human lifespan Tejas Menon, Hayley A. McQuilten, Jerome Samir, Thi H.O. Nguyen, Ratana Lim, Jasveen Kaur, Simone Rizzetto, Auda Eltahla, Paul G. Thomas, Martha Lappas, Jamie Rossjohn, Stephanie Gras, Jane Crowe, Katie L. Flanagan, Fabio Luciani, Peter C. Doherty, Carolien E. van de Sandt and Katherine Kedzierska

Central memory T-cells with largely unchanged TCR repertoires and gene expression profiles dominate influenza-specific CD8+ pools across human lifespan

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