Dataset for Topical Mitomycin C Application Versus Intralesional Corticosteroid Injection in the Management of Caustic Esophageal Strictures in Pediatrics: A Randomized Controlled Trial
Description
This dataset supports the randomized controlled trial titled “Topical Mitomycin C Application Versus Intralesional Corticosteroid Injection in the Management of Caustic Esophageal Strictures in Pediatrics” conducted at the Pediatric Surgery Department, Ain Shams University Hospitals, between May 2022 and July 2025. The dataset includes anonymized clinical information from 38 pediatric patients with caustic esophageal strictures. Collected variables include demographic data, type of corrosive substance ingested, dysphagia score (DS), stricture length, follow-up outcomes, and complications. Data were recorded and analyzed using Microsoft Excel (.xlsx). Ethical approval was obtained from the Institutional Review Board at Ain Shams University (Approval No. 00006379), and all patient identifiers were removed prior to data inclusion. This dataset may be valuable for comparative treatment outcome studies focusing on pediatric caustic esophageal stricture management and for meta-analyses of minimally invasive treatment strategies.
Files
Steps to reproduce
1.Pediatric patients with caustic esophageal strictures were prospectively enrolled and randomized into two treatment groups: topical Mitomycin C application and intralesional corticosteroid injection. 2.For each patient, demographic data, type of corrosive substance, dysphagia scores (initial and final), stricture length, number of dilatations, follow-up duration, and complications were recorded. 3.The primary outcome was dilatation success, defined as complete or marked clinical improvement (dysphagia score 0 or 1) at study completion. 4.Data were entered and processed using Microsoft Excel, then analyzed using SPSS version 27 (IBM Corp., Armonk, NY). 5.The Mann–Whitney U test was applied for non-parametric comparisons between groups. Chi-square or Fisher’s exact test was used for categorical variables, and linear-by-linear association was applied for ordinal data. 6.A p-value < 0.05 was considered statistically significant. 7.To reproduce the results, users can group data by the variable Treatment_group (Steroid vs. MMC) and compare dysphagia score improvement, periodic dilatation index, dilatation frequency and complication rates using the same statistical tests.
Institutions
- Ain Shams University Hospital