Dynamic rearrangement of cell states detected by systematic screening of sequential anticancer treatments

Name: Dynamic rearrangement of cell states detected by systematic screening of sequential anticancer treatments
Creator: Simon Koplev
Published: 2020-07-01T20:13:21.667Z
Keywords: Cancer, Markov Chain Monte Carlo, Cancer Chemotherapy, Bayesian Method, Drug Combination

Koplev, Simon; Longden, James; Ferkinghoff-Borg, Jesper; Linding, Rune

doi:10.17632/wgybvcvjwf.7

Dynamic rearrangement of cell states detected by systematic screening of sequential anticancer treatments

Published: 1 July 2020| Version 7 | DOI: 10.17632/wgybvcvjwf.7

Contributors:

Simon Koplev, James Longden, Jesper Ferkinghoff-Borg, Rune Linding

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Modeled data generated by a Bayesian dose-response framework predicting sequentially effective drug combinations from an oncological drug matrix screen, comprising 10,000 drug combinations in melanoma and pancreatic cancer cell lines.

Dynamic rearrangement of cell states detected by systematic screening of sequential anticancer treatments

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