Outcomes of Balloon Angioplasty in Infants with Simple or Complex Recurrent Coarctation of the Aorta Raw Dataset
Description
Recurrence of coarctation of the aorta (CoA) is a relatively common complication following surgical correction in neonates. Balloon angioplasty is the favored treatment for recurrent CoA in infancy and early childhood, but persistent or recurrent obstruction remains a challenging complication. This retrospective cohort study aims to assess outcomes of balloon angioplasty for infants with recurrent CoA based on the complexity of cardiac defects at the time of surgical intervention. Data were analyzed from patients at a single tertiary care center who underwent balloon angioplasty for recurrent CoA within their first year of life between 2002-2021. A total of 41 patients were included and separated into simple (n = 26) or complex (n = 15) cohorts based on the coexisting cardiac defects present. These cohorts were similar in age, weight, sex, and time since initial surgical repair. The complex cohort had a significantly higher rate of subsequent coarctation re-intervention within a 2-year follow-up period (73% vs. 31%, p = 0.003, RR = 2.4; 95% CI = 1.2-4.6, p = 0.003). Our findings suggest that recurrent CoA in the presence of additional complex cardiac congenital heart disease may not be as amenable to balloon angioplasty in infants and should be considered when counseling patient families.
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Institutions
- Mayo Clinic Rochester