Intergrated Multi-omics Sequencing Reveals Metabolic Reprograms in the Progression of ccRCC

Published: 26 June 2023| Version 1 | DOI: 10.17632/x4krt22tf4.1
Contributor:
Junyi Hu

Description

100 samples from treatment-naive ccRCC patients and 50 matched normal adjacent tissues (NATs) were profiled with whole exon sequencing (WES), whole transcriptome sequencing (WTS), data-independent acquisition (DIA)-based proteome and untargeted metabolome technology to identify the general molecular characteristics of the TJ-RCC cohort. Single-nucleic RNA sequencing, single-nucleic multiome, spatial transcriptome and spatial metabolome were performed on part of these 100 tumors to detail the ITH inside ccRCC.

Files

Institutions

Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology

Categories

Cancer, DNA Sequencing, Renal Cell Carcinoma, Single-Cell RNA Sequencing

Licence