Track data for OTI T cell migration in the brain during T. gondii infection
Published: 28 June 2023| Version 1 | DOI: 10.17632/x9s7hymx8h.1
Contributor:
Tajie HarrisDescription
The data contained in this spreadsheet are of the -x, -y, and -z coordinates of fluorescent T cells migrating in the brains of Toxoplasma gondii infected C57BL/6 mice. Mice were infected with a parasite strain expressing ovalbumin (Pru-OVA) for four weeks. Activated GFP-expressing OT-I T cells were transferred to the mice and imaged by multiphoton microscopy seven days later. Microscopy was performed on explanted brain as described in Harris, et al. Nature. 2012. In this dataset, each T cell has a track ID that corresponds to a single cell. The three-dimensional coordinates are provided along with the corresponding time series.
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Institutions
University of Pennsylvania, University of Virginia
Categories
Brain, Cell Migration, Cytotoxic T-Cell, Toxoplasma gondii