A Study of PD-L1-mediated immune evasion in triple-negative breast cancer is linked to the loss of ZNF652, Liu et al

Published: 31 August 2023| Version 1 | DOI: 10.17632/xf98wxm3t5.1
Contributor:
Yuncheng Liu

Description

In this study, we find that ZNF652 recruites the NuRD complex to act as a potent transcription repressor of PD-L1. Suppressed ZNF652 expression in TNBC unleashes PD-L1-mediated immune evasion both in vitro and in vivo. The provided dataset comprises a raw data containing all original blot images in our study to support our hypothesis.

Files

Institutions

Peking University

Categories

Western Blot

Licence