A Study of PD-L1-mediated immune evasion in triple-negative breast cancer is linked to the loss of ZNF652, Liu et al
Published: 31 August 2023| Version 1 | DOI: 10.17632/xf98wxm3t5.1
Contributor:
Yuncheng LiuDescription
In this study, we find that ZNF652 recruites the NuRD complex to act as a potent transcription repressor of PD-L1. Suppressed ZNF652 expression in TNBC unleashes PD-L1-mediated immune evasion both in vitro and in vivo. The provided dataset comprises a raw data containing all original blot images in our study to support our hypothesis.
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Institutions
Peking University
Categories
Western Blot