Bile acids mediate liver-bone marrow crosstalk. Vitale et al.

Description

This dataset accompanies the manuscript "Bile acids mediate liver-bone marrow crosstalk" (Esmaili et al., iScience). It contains mouse-derived source data and R code underlying the paper's figures. Source data: Flow cytometry — bone-marrow HSPC compositions from the xenograft tumor study, the 4-diet study, and the SC-435 intervention… Phenotypic measurements, qPCR readouts, bile-acid measurements (UPLC–MS)… R code: flow cytometry preprocessing/clustering, RNA-seq DGE/GSEA, bile-acid composition analysis. README inside maps scripts to figure panels. Six-diet flow cytometry data are deposited separately under Mendeley DOI 10.17632/sfng2h249n.3. Raw RNA-seq reads are deposited at NCBI GEO under GSE325236 (xenograft) and GSE325237 (six-diet).

Institutions

• Westmead Institute for Medical Research

  New South Wales, Sydney
• The University of Sydney

  New South Wales, Sydney

Categories

Funders

• National Health and Medical Research Council

  Department of Health and Aged Care

  Canberra

  Grant ID: APP1149976, APP1107178, APP1145766, APP1196492

Licence