Role of Pyroptosis in Pterygium Pathogenesis and Regulatory Effects of Mesenchymal Stem Cell-Derived Exosomes on Fibroblast Pyroptosis: A Mechanistic Study

Published: 24 September 2026| Version 1 | DOI: 10.17632/xyn7st52hw.1
Contributor:
SHU ZHANG

Description

The raw data include Western blot, qRT-PCR, immunohistochemistry/immunofluorescence, and CCK-8 assays. These data show that NLRP3, ASC, caspase-1, and GSDMD were upregulated in pterygium tissues and H₂O₂-stimulated HPFs, while hEs-MSCs-Exo restored HPF viability and downregulated these pyroptosis-related markers, supporting inhibition of the NLRP3/ASC/caspase-1/GSDMD pathway.

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Pterygium, Pyroptosis, Exosome

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