Cell atlas of the regenerating human liver after portal vein embolization

Published: 9 August 2021| Version 1 | DOI: 10.17632/yp3txzw64c.1
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Description

Processed single-cell and single-nucleus RNA-seq data for "Cell atlas of the regenerating human liver after portal vein embolization". Original in https://www.biorxiv.org/content/10.1101/2021.06.03.444016v1. Data is deposited as RDS files, RData, and a csv file. The RDS/RData contain Seurat v3 objects. Full list of author contributions can be found in the associated manuscript. Brief description of data files: - allcells_css_annot.rds - Seurat containing all cells (scRNA-seq), along with various annotations (see figs 2 and 5 in the associated manuscript). - hep_zonation_metadata.csv - Table in csv format containing inferred zonation values for hepatocytes. Can be combined with hepatocytes from the previous file. - endothelial_cells_annot.rds - Seurat containing only the endothelial cells, and including more annotation of those populations (see fig 4 in the associated manuscript). - frozen_tissue_dataset.rdata - Seurat containing all nuclei (snRNA-seq) and corresponding annotations (see fig 1 of the associated manuscript)

Files

Steps to reproduce

Files presented are the final products of the analysis described in the manuscript with the same name. For more information on data generation and analysis, refer to the Methods section of the manuscript and see https://github.com/tomasgomes/liver_regen.

Institutions

Eidgenossische Technische Hochschule Zurich Department of Biosystems Science and Engineering

Categories

Liver, Transcriptomics, Cell Regeneration, Human

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