Raw data: Manganese associated with hyaluronic acid against the cytotoxicity induced by Bothrops jararacussu venom in Rattus norvegicus L6 myoblast cells
Description
This dataset contains in vitro experimental data evaluating the cytoprotective effects of manganese (Mn²⁺), alone or associated with hyaluronic acid (HA), against cytotoxicity induced by Bothrops jararacussu venom (Bjssu) in L6 rat myoblast cells (Rattus norvegicus). Cell viability was assessed by MTT assay at different exposure times (1, 2, 3, 6, 12, and 24 h) using varying concentrations of venom (1.25 and 2.5 μg/mL) and manganese (1, 2, and 4 mM), with or without HA (2500 μg/mL). The dataset also includes IC50 determination, morphological analyses by light microscopy, and statistical analyses of cell viability. These data support investigations into complementary therapeutic strategies aimed at reducing local tissue damage caused by snakebite envenomation.
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- Research Incentive Plan of Pontifical Catholic University of São Paulo (PIPEq – PUC/SP)Grant ID: no. 25238-2022/2