Conformational transitions and activation of the adhesion receptor CD97

Published: 4 December 2023| Version 1 | DOI: 10.17632/zhjwhfnd77.1
Contributor:
Yan Zhang

Description

CD97, also known as ADGRE5, is the first cloned human aGPCR that belongs to the epidermal growth factor (EGF) seven-transmembrane family of aGPCRs (now called ADGRE family). We reported the cryo-electron microscopy structures of human CD97 in its inactive apo and G13-bound fully active states. Here, we present SDS-PAGE analysis results for the purified inactive CD97 and CD97-G13 complex.

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Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis

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