STT3A is essential for Wnt signaling and represents a target for cancers driven by RNF43 deficiency

Published: 13 October 2025| Version 2 | DOI: 10.17632/ztg7pxr6ch.2
Contributor:
Zhengjin He

Description

This dataset contains the original raw and analyzed data supporting the manuscript “STT3A is essential for Wnt signaling and represents a target for cancers driven by RNF43 deficiency”. The study identifies STT3A as an essential regulator of the Wnt signaling pathway and a potential therapeutic target for RNF43-deficient cancers. Included data were generated from key experiments, including Wnt reporter assays (DDT), Western blotting (WB), and CRISPR screen, and other experiments central to the study

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Steps to reproduce

All data were derived from the study "STT3A is essential for Wnt signaling and represents a target for cancers driven by RNF43 deficiency", and detailed methods have been described.

Institutions

  • Shanghai Institute of Biochemistry and Cell Biology

Categories

Cell Biology

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