Toxicon

Data for short-term, subchronic toxicity and the teratogenic potential of Rhopalurus junceus scorpion venom by oral route in mice. Short-term oral toxicity was test in both sexes NMRI mice that received 100 mg/kg/day of scorpion venom extract for 28 days. For the subchronic study, mice were administered with three doses (0.1, 10, and 100 mg/kg) by oral route for 90 days. Teratogenic potential was tested in pregnant mice administered from day 6 to 15 post conception. Significant differences were observed in body weight and food intake of animal treated for short-term and subchronic assays. Variations in serum urea and cholesterol were observed after 90 days oral treatment. Spontaneous findings not related to the treatment were reveal in histology evaluation. Exposure in pregnant mice did not produce maternal toxicity. Signs of embryo-fetal toxicity were not observed. The current study provides evidence that exposure to low or moderate dose of Rhopalurus junceus scorpion venom by oral route did not affect health of animals and has low impact on reproductive physiology.

All raw data related to the experiments conducted in this work, the name refer to the figures on the paper

This is the supporting raw data and information behind the published paper "Speedy milking of fresh venom from Aculeate hymenopterans" by Fox et al. (2018), available at: https://www.sciencedirect.com/science/article/pii/S0041010118300990 It includes: - Draft version of the manuscript prior to submission; - Peer review details; - Raw chromatograms obtained for centrifuge-milked venoms of fire ants, two species of bees, one species of Asian hornet; - Raw chromatograms of internal and calibration standards; - Images and details on the identification of utilised insects; - Pictures obtained for the venoms extracted and utilised structures. Disclaimer: The presented method for venom extraction is extremely simple, and can be extended to other poisonous animal through simple adaptations. Such secretions can be highly dangerous. Responsible use of this technology is strongly recommended. Venom obtained via such method is to be used for legal, surveilled scientific purposes **only**.