Gynecologic Oncology

De-identified uterine serous carcinoma patients' gene expression information and clinicodemographic information.

Protocol and SAP

Statistical analyses as we ran it using Stata v15.1. The .do file can directly be used in Stata, but for researchers who don’t have Stata, we added our programming in a .txt file too. We do not have permission to share the database itself: this would be a violation of ethics. Licence CCo 1.0 chosen randomly from the licence list, none of those were used in our data analysis.

These are the raw data of the PC12 assay. PC12 cells were stimulated with exosomes purified from various different cervical cancer cell lines. PC12 cells were stained with an anti-beta3-tubulin antibody and neurite outgrowth quantified. The positive control was PC12 cells treated with recombinant NGF (nerve growth factor) and negative control was untreated PC12 cells.

Summary results for association of 11 million single nucleotide polymorphisms with epithelial ovarian cancer in Asian women. OBJECTIVE: Genome-wide association studies (GWASs) for epithelial ovarian cancer (EOC) have focused largely on populations of European ancestry. We aimed to identify common germline variants associated with EOC risk in Asian women. METHODS: Genotyping was performed as part of the OncoArray project. Samples with >60% Asian ancestry were included in the analysis. Genotyping was performed on 533,631 SNPs in 3238 Asian subjects diagnosed with invasive or borderline EOC and 4083 unaffected controls. After imputation, genotypes were available for 11,595,112 SNPs to identify associations. Please refer to the README file in 'AsianResultsChr9_X' for more information.