Journal of the American Academy of Dermatology

This is a supplemental methods section that demonstrates the two models used in our manuscript for external validation. The two models replicate the multivariable models proposed in the manuscript by Weinkle et al., which were formulated via stepwise regression selecting 4 predictor variables. The first model with the presence or absence of Nikolsky sign, atypical target, fever, and lymphopenia (Supplemental Figure 1). The second model with the presence or absence of Nikolsky sign, atypical target, fever, and mucosal involvement (Supplemental Figure 2). In order to externally validate these models, either a value of 1 (if present) or 0 (if absent) was plugged into the equation for each characteristic of each patient in our retrospective cohort. The value of the probability of SJS/TEN was documented and used in the validation efforts. .

This is a supplemental methods section that demonstrates the two models used in our manuscript for external validation. The two models replicate the multivariable models proposed in the manuscript by Weinkle et al., which were formulated via stepwise regression selecting 4 predictor variables. The first model with the presence or absence of Nikolsky sign, atypical target, fever, and lymphopenia (Supplemental Figure 1). The second model with the presence or absence of Nikolsky sign, atypical target, fever, and mucosal involvement (Supplemental Figure 2). In order to externally validate these models, either a value of 1 (if present) or 0 (if absent) was plugged into the equation for each characteristic of each patient in our retrospective cohort. The value of the probability of SJS/TEN was documented and used in the validation efforts. .

Supplemental figures: 1. Disposition of participants 2. Participants with at least a 1-point improvement in glabellar line severity 3. Participants with improvement on global aesthetic improvement scale 4. Duration of improvement in glabellar line severity before return to baseline levels 5. Participant global satisfaction at week 4 Supplemental tables: 1. Efficacy and satisfaction rating scales 2. Key eligibility criteria for study participation 3. Baseline demographics 4. Summary of glabellar line response duration data

Supplement to Methods in "Development and Implementation of an Order Set to Improve Value of Care for Patients with Severe Stasis Dermatitis: Journal of the American Academy of Dermatology 2018