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- Data for: hENT1 Reverses Chemoresistance by Regulating Glycolysis in Pancreatic Cancer.These data include the original data of in vitro and in vivo experiments. "P VS PR" means: comparing results between GEM-resistant pancreatic cancer cells and their parental sensitive ones. "TOTAL" means: comparing results among GEM-resistant pancreatic cancer cells, parental sensitive pancreatic cancer cells and the two cells transfected with lentivirus carrying Lv-hENT1 plasmid. GEM- group and GEM+ group were set in all experiments. In vitro tests, GEM+ group means: cells treated with 33.3nmol/L GEM in medium for 24h. In vivo tests, GEM+ group means: BALB/c nude mice treated with 3.33nmol/kg GEM by oral every other day after tumorigenesis for 4 times.
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- Data for: Inhibition of hydrogen sulfide synthesis reverses acquired resistance to 5-FU through miR-215-5p-EREG/TYMS axis in colon cancer cellsMiRNA sequencing was performed after knock down CBS in HT-29 and DLD-1 cell lines.
- Dataset
- Repurposing Cabozantinib to GISTs: Overcoming Multiple Imatinib-Resistant cKIT Mutations Including Gatekeeper and Activation Loop Mutants in GISTs Preclinical ModelsKIT mutations inhibitory activity in BAF3 cellsIn vivo anti-tumour efficacy
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- Tubulin-RB3_SLD-TTL in complex with SB226
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- A novel anti-tumor agent S-40 in complex with tubulin
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- Crystal structure of Z. mays CK2alpha in complex with the ATP-competitive inhibitor 4-[(E)-(fluoren-9-ylidenehydrazinylidene)-methyl] benzoate
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- Crystal structure of human CK2alpha in complex with the ATP-competitive inhibitor 4-[(E)-(fluoren-9-ylidenehydrazinylidene)-methyl] benzoate
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- Structure of p21-activated kinase 4 with a novel inhibitor KY-04031
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- Crystal structure of human galectin-1 in complex with lactobionic acid
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- Crystal structure of human galectin-1 in complex with thiodigalactoside
- Dataset