The pharmacological and ethnopharmacological data included refer to 64 Hypericum species distributed in China.

Raw data: Anti-nociceptive and anti-inflammatory effects of the ethanol extract of Arenga pinnata (Wurmb) Merr. fruit

The influence of laboratory isolated and identified SME, ASME and IFBp, from Barleria prionitis aerial part, on the production and release of pro-inflammatory mediators i.e. myeloperoxidase (MPO), elastase, matrix metalloproteinase 9 (MMP-9), interleukin 8 (IL-8), tumor necrosis factor alpha (TNF-α) and leukotriene B4 (LTB4) was evaluated in the formyl-met-leu-phenylalanine (f-MLP) and lipopolysaccharide (LPS) stimulated human neutrophils using ELISA reader. Both SME and ASME were isolated and characterized from the IFBp. SME was isolated as white amorphous powder melted at 120–121°C with UV (MeOH) λmax, 236 nm; IR (KBr) nmax, 3404 cm–1 (–OH), 1687 cm–1 (ester carbonyl), 1645 cm–1 (enol–ether system) and positive ESI-MS, m/z (rel. int.): 835 [2M+Na]+ (8); 445 [M+K]+ (8); 429 [M+Na]+ (100), (C17H26O11 requires 406). While ASME was isolated as colorless crystals melted at 180–181°C with UV (MeOH) λmax, 235 nm; IR (KBr) nmax 3400 cm–1 (–OH), 1701 cm–1 (ester carbonyl), 1635 cm–1 (enol–ether system) and positive ESI-MS, m/z (rel. int.): 919 [2M+Na]+ (12), 487 [M+K]+ (8), and 471 [M+Na]+ (100) (C19H28O12 requires 448). Identity of SME and ASME was confirmed by comparison of their spectral analysis data (UV, FTIR, 1H NMR and 13C NMR, and positive ESI-MS) with that reported in the literature (Ghule et al., 2012; Damtoft et al., 1982; Taneja and Tiwari, 1975). Fig. 1 depicts the chemical structures of these laboratory isolated and identified compounds and the supplementary spectral data is shown in Fig. S1 (UV VIS spectra), Fig. S2 (FTIR spectra), Fig. S3 (1H-NMR spectra), Fig. S4 (13C-NMR spectra), Table S1 (1H- and 13C-NMR spectral data), Fig. S5 (positive ESI-MS spectra) of SME and ASME isolated and characterized from IFBp. Using SME and ASME as laboratory isolated and identified marker compounds of B. prionitis, a HPTLC method was validated following the guidelines of the International Conference on Harmonization.

Data File 1: Toxicity study in rat model Data File 2: Behavioural study in zebrafish model

13 ginsenosides were screened out, of which 6 sulfonated products of ginsenosides were detected, they were R1-SO3 (m/z, 1059.53), Re-SO3 (m/z, 1025.55), Rg1-SO3 (m/z, 878.47), Ro-SO3 (m/z, 1035.32), Rb1-SO3 (m/z, 1179.58), and Rk3-SO3 (m/z, 745.40). The sulfonated products of Rf, Rd, ZBS R1, F4, Rh2, Rk1 and Rg5 were not detected in SF-PQR.

Data matrices used in regression analysis, Bayesian analysis and IDM analysis of the African flora and African medicinal flora

Supporting data for identification of isolated compounds.

1. Raw Data information on antimalarial activity 2. Spectra information on isolated compounds

The mushroom Ganoderma lucidum (G. lucidum) is a traditional Chinese medicine reported to have a variety of pharmacological properties, including anti-cancer activity[1,2]. G. lucidum spore oil (GLSO) is a lipid substance extracted from sporoderm-broken spore of G. lucidum. Here, Data were provided on the effect of GLSO on apoptosis in breast cancer cells in vitro. As model systems, 4T1, MCF-7 and MDA-MB-231 breast cancer cell lines were used to verify the effect of GLSO on breast cancer cell proliferation. The cells were treated with various concentrations of GLSO (0.2, 0.4 and 0.6 μL/mL) for different time intervals (24, 48 and 72 hours), and measured cell viability was assessed by Trypan blue staining. Further, The results of early apoptosis and late apoptosis of MDA-MB-231 cells induced by GLSO (0.2, 0.4 and 0.6 μL/mL) for different time intervals (24 and 48 hours) in vitro by fluorescence activated cell sorting (FACS) analysis. This data article is part of a study Jiao et al., 2019 Jun, where detailed interpretation and discussion can be found.

Experimental data on the neuroprotective effects of ANNAO tablets in cerebral ischemia-reperfusion injuries.