Journal of Ethnopharmacology

The mushroom Ganoderma lucidum (G. lucidum) is a traditional Chinese medicine reported to have a variety of pharmacological properties, including anti-cancer activity[1,2]. G. lucidum spore oil (GLSO) is a lipid substance extracted from sporoderm-broken spore of G. lucidum. Here, Data were provided on the effect of GLSO on apoptosis in breast cancer cells in vitro. As model systems, 4T1, MCF-7 and MDA-MB-231 breast cancer cell lines were used to verify the effect of GLSO on breast cancer cell proliferation. The cells were treated with various concentrations of GLSO (0.2, 0.4 and 0.6 μL/mL) for different time intervals (24, 48 and 72 hours), and measured cell viability was assessed by Trypan blue staining. Further, The results of early apoptosis and late apoptosis of MDA-MB-231 cells induced by GLSO (0.2, 0.4 and 0.6 μL/mL) for different time intervals (24 and 48 hours) in vitro by fluorescence activated cell sorting (FACS) analysis. This data article is part of a study Jiao et al., 2019 Jun, where detailed interpretation and discussion can be found.

The supplementary materials file includes LC-MS/MS result, transcriptome analysis result and differentially expressed gene predicted PPI result.

NMR of essential oils from different morphological parts of Dennettia tripetala Baker f. GC-MS chromatogram of D. tripetala oil GC-MS of β-Phenylnitroethane (BPNE) sub-fraction GC-MS of purified β-Phenylnitroethane

NMR data Figure S1-S4 of 1H and 13C NMR spectra for compounds isosessein (1) and sessein (2). Figure S5-S6 HMBC spectra for compounds isosessein (1) and sessein (2).

All data are expressed as the mean ± SD. The data in toxicity test comparisons among different groups were performed by analysis of variance using an ANOVA test and SAS 9.3 statistical software. The experimental results of traditional pharmacological activities analyzed using the Student's t-test and SAS 9.3 statistical software.

Data File 1: Toxicity study in rat model Data File 2: Behavioural study in zebrafish model

Background: Senecio biafrae is a medicinal plant widely used in traditional medicine to cure female infertility. Some effects have been pharmacologically demonstrated on immature female rats but in vivo and in vitro investigations are still necessary for determining its mechanism of action. The aim of the present study was to evaluate the estrogenic and FSH-like effects of the plant extracts and fractions on some fertility parameters in immature female rats and on in vitro survival and growth of swine preantral follicles.

IR (CDCl3) of Glaucacetalin E (1), 1HNMR (CDCl3, 500 MHz) of Glaucacetalin E (1), 13CNMR (CDCl3, 125 MHz) of Glaucacetalin E (1), DEPT (CDCl3, 125 MHz) of Glaucacetalin E (1), COSY (CDCl3, 500 MHz) of Glaucacetalin E (1), HSQC (CDCl3, 500 MHz) of Glaucacetalin E (1), HMBC (CDCl3, 500 MHz) of Glaucacetalin E (1), HMBC (CDCl3, 500 MHz) of Glaucacetalin E (1). IR (CDCl3) of Galphimidin B (2), 1HNMR (CDCl3, 500 MHz) of Galphimidin B (2), 13CNMR (CDCl3, 125 MHz) of Galphimidin B (2), DEPT (CDCl3, 125 MHz) of Galphimidin B (2), COSY (CDCl3, 500 MHz) of Galphimidin B (2), HSQC (CDCl3, 500 MHz) of Galphimidin B (2), HSQC (CDCl3, 500 MHz) of Galphimidin B (2), HMBC (CDCl3, 500 MHz) of Galphimidin B (2), HMBC (CDCl3, 500 MHz) of Galphimidin B (2). X-Ray crystallography of Galphimidin B (2, CCDC 1949476). Table 1S. Crystal data and structure refinement for cu_galphimin B (2, CCDC 1949476)_0m.

NMR spectra of bis-iridoids from Pterocephalus hookeri

Supplementary Table 1. 99 targets of shikonin from different databases. Supplementary Table 2. 1219 genes associated with proteinuria from different databases. Supplementary Table 3. candidate targets with therapeutic glioma. Supplementary Table 4. 1083 pairs of protein interactions of candidate targets. Supplementary Table 5. specific analytical parameters of 41 central targets.