European Journal of Pharmaceutical Sciences

The SIMCA file for Predictive Identification of Co-formers in Co-amorphous Systems

The research data files are compromise of 5 supplementary materials. The detailed information of clinical study is displayed in Supplementary material 1, and all simulated data in manuscript are shown in supplementary material 2-5: 1) supplementary material 1 (the detailed information of clinical study) 2) supplementary material 2 (the simulated data used for internal verification of PBPK model) 3) supplementary material 3 (the simulated data used for external verification of PBPK model) 4) supplementary material 4 (the simulated data used in the section 4.3 of manuscript) : this simulated data was used to explore whether the rapid dissolution rate (dissolved ≥ 85% in 30 min) are necessary to ensure the bioequivalence for BCS I class drug 5) supplementary material 5 (the simulated data used in the section 4.4 of manuscript) : this simulated data was used to establish a clinically relevant dissolution specification of Isosorbide Mononitrate tablets.

LC-MS data of mouse urine used for Metabomoic analysis

This is our raw data, we are using this data to get the model

INR-Specific Incidence of All Adverse Events (All Episodes of Thromboembolism and All Major Bleeding Episodes)

The rheological profile of a semi-solid product is a critical quality attribute. To monitor changes of this attribute during manufacturing, it would be beneficial to measure the rheological parameters in an on-line or in-line mode and implement this as a part of a control strategy for manufacturing of semi-solids. An automated system based on the measurement of pressure difference across both a topology optimised shape and a tube geometry (capillary viscometer) was investigated. The Pressure Difference Apparatus (PDA) can sample from the bulk intermediate/product stream and press the sample through the apparatus at different flow rates to yield a frequency sweep (G’ and G’’) and a flow curve (viscosity).

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.