Cancer Cell

This dataset contains a number of zip folders, grouping information relevant to reproduce key items and figures of our study: Stammnitz, M.R. et al. "The origins and vulnerabilities of two transmissible cancers in Tasmanian devils". Cancer Cell 33(4), 607-619 (2018).

Raw data from Delloye-Bourgeois et al., Cancer Cell, 2017

The zip file contains three folders, which group somatically acquired indels, structural variants and substitutions. Within each of these folders, there are individual tab-delimited text files containing the calls for each patient separately, together with which samples within each patient the mutation was identified in. Data arise from whole genome sequencing of primary and metastatic / relapsing breast cancers.

Matlab script that allows the integration and sum of the [1-13C] pyruvate peaks and [1-13C] lactate peaks over the acquisition time when using MRI after the injection of hyperpolarized [1-13C] pyruvate.

1. Main and supplementary raw data. Zip folder with 7 Excel files containing the raw measurements of main FILE 1 figures 1 (1A,!b,1C,1D,1F,1G,1H,1I), FILE 2 figure 2 (2A,2B,2D,2E,2F), FILE 3 figure 3 (3A,3B,3C,3D,3E,3F,3G), FILE 4 figure4 (4A,4B,4C,4D,4E,4F,4G,4H,4I,4J), FILE 5 figure 6 (6A,6B,6C,6D,6E,6H,6I), FILE 6 figure 7 (7B,7C,7D,7E,7F,7G,7H,7I,7J) and FILE 6 supplementary raw data (Supplementary 1A,1C,2A,2C,2D,2E,2F,2G,3A,3C,3D,3E,3F,3G,4A,4B,4C,4E,4G,5D,5E) 2. Raw CT and PET data. Zip folder containing the raw DICOM data for the in vivo 18FFDGPET uptake and associated CT experiments. 3. Raw MRI data. Zip folder containing the raw DICOM data for the in vivo 1-13C hyperpolarized pyruvate - MRI experiments. 4. Raw Western Blot data. Folder containing the original blots pasted on pdf for figures 1, 2, 3, 4 (in 3 docs 4I, 4II, 4III), 6 and 7; and supplementary figures S2,S3,S4 and S5. See the main manuscript for more details (Open access).