mBio

This dataset contains the raw data supporting main Figures 1-5 and Supplementary Figures 1, 2, 3, 4, 6 used in the manuscript "Fc-engineered antibodies enhance protection against SARS-CoV-2 lung infection and inflammation" submitted to mBio. The dataset includes viral RNA and infectious virus titers of mice treated with control antibodies or S309 monoclonal antibodies given either before or after SARS-CoV-2 infections. The dataset also includes flow cytometry analysis, lung ventilation analysis, lung pathology, RNA sequencing analysis, weight loss measurement, and antibody titers of treated mice. Some in vitro characterization of antibodies was generated using Jurkat cells.