Chemosphere

Bisphenol A (BPA) and Diethylhexyl Phthalate (DEHP) are well-studied, endocrine disrupting chemicals (EDCs), however, the effects of mixtures of these EDCs are not. To assess the consequences of prenatal exposure to a mixture of these EDCs, dams were orally administered either saline (control), BPA (5μg/Kg BW/day), low-dose (LD) DEHP (5μg/Kg BW/day), high-dose (HD) DEHP (7.5 mg/Kg BW/day), or a combination of BPA with LD- or HD-DEHP. Gestational weights, number of abortions, litter size and weights, number of live births and stillbirths were recorded. Morphometric measures were obtained at birth and body weight, food and water intake were monitored weekly from postnatal weeks 3-12. Offspring were sacrificed at 16-24 weeks of age and organs were dissected and weighed. The abortion rate of dams exposed to HD DEHP and the mixtures, B+LD-D and B+HD-D were higher at 9, 14 and 27% respectively. Prenatal exposure to BPA or HD DEHP significantly decreased relative thymus weights in male but not female offspring at 16 weeks. Terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labelling (TUNEL) was performed in thymus tissues. Apoptotic cells were detected in thymus sections of offspring prenatally exposed to DEHP. Relative heart weights increased in B+HD-D exposed male offspring compared to the other groups. The results indicate that a mixture of BPA and DEHP, produced a pronounced effect on pregnancy outcomes. Male offspring appear to be more susceptible to the programming effects of these EDCs or their mixture suggesting a need to reconsider the possible additive, antagonistic or synergistic effects of EDC mixtures.

Continuous changes of zebrafish OC and CR during 360 h Tl exposure

Raw data of Cd, Hg and Se in sharks Sphyrna lewini

The data for the efficient decomposition of toxic sodium cyanate by hematite catalyst

The database were from the Chinese Longitudinal Healthy Longevity Study (CLHLS), which is an ongoing perspective survey conducted in longevity areas in China. The details of this survey have been described in a previous work 18. The data used in this study were obtained from the fifth wave of the CLHLS conducted in 2009 because this wave was the first to conduct detailed health exams and collect biosamples, in addition to interviews, similar to other surveys. A total of 461 elderly people aged ≥90 years from Xiayi County of Henan Province, Sanshui District of Guangdong Province, Zhongxiang City of Hubei Province, Yongfu County of Guangxi Province, and Mayang County of Hunan Province were included in this study.

Data base and python script for AhR Agonism modeling

This file contains all raw data associated with generating acute:chronic ratio's for this manuscript. Data comes from the Envirotox database, a proprietary algal database and REACH.

Data of Mechanisms and pathways of ethidium bromide Fenton-like degradation by reusable magnetic nanocatalysts

Locations of sampling stations, water depth, grain size and 210Pbex, 226Ra and 238U activities, Pu isotopes activities and 240Pu/239Pu atom ratiosin the BS and NYS surface sediments during 2014.

The ratios between concentrations in the maternal and cord serum, and related data.