Pathology - Research and Practice

This dataset contains TCGA data for lung cancer and qRT-PCR data for tissue samples.

This study aims to clarify the relationship between cognitive dysfunction and hyperhomocysteinemia (HHcy) in mice. Although this relationship has been frequently observed in previous studies, the molecular mechanisms underpinning cognitive impairment during HHcy remain unclear. HHcy is a common metabolic disorder in humans, and the results of the present study may support better clinical decision making in cases where cognitive impairment has been diagnosed. Here, we present evidence that mice with induced HHcy have increased autophagy, apoptosis, synaptic remodeling, and downregulation of Hes1 and Hes5 in their brains compared to those of control mice. This supports the theory that HHcy-mediated remodeling of the brain causes cognitive dysfunction.

EGFR mutation abundance of 413 real-time PCR positive cases which were verified by next-generation sequencing technology

Tumor samples were collected from 121 esophageal cancer patients who were diagnosed histologically at the Anyang tumor hospital, Henan, China.

raw data

Raw data and Fisher's Exact Test on contingency tables: Intraductal carcinoma of the prostate vs. Invasive adenocarcinoma of the prostate Gleason 5 with tumor necrosis

the clinicopathological characteristics of patients and the expression of LINC01939 in our cohort