International Journal of Oral & Maxillofacial Surgery

Raw data was added

Objective: to evaluate nicotine patch effectiveness in the control of pain, edema and trismus in lower third molar surgery. Materials and Methods: A prospective, randomized, triple blind split-mouth trial was performed wiih 20 patients who underwent two surgical procedures at different times. In the control intervention, a nicotine patch without the active principle was used (placebo), whereas a patch containing 14 mg nicotine was used in the experimental group. Results: It was observed that the nicotine patch was effective in pain control at 4 and 8 hour intervals with values of p = 0.023 and p = 0.005, respectively. The adhesive patch containing the active principle also showed significant statistical results for edema control in the first 24 hours (p = 0.004), 48 hours (p = 0.005), 72 hours (p = 0.007) and 7 days (p = 0.046) following the intervention. Postoperative mouth opening was significantly higher at 72-hour and 7-day intervals in patients who received the nicotine patch. The amount of rescue analgesics was lower when the patch was used (p = 0.026) and the level of satisfaction was statistically relevant for interventions which included the active principle (p = 0.008). Conclusion: The nicotine patch was effective in controlling pain, edema and trismus.

This data contains data from the cadaver experiment. 1. lymph node count from endoscopic assisted selective neck dissection from unilateral neck 2. Elapsed time for preparation (which includes establishing working space) and endoscopic assisted selective neck dissection