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- Data for: New skin care application of PLGA NP possessing accelerated production of type 17 collagenConference presentation data
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- Data for: Transfersomal nanoparticles for nose-to-brain delivery of ofloxacin for better management of bacterial meningitis: formulation, optimization by Box-Behnken design, characterization and in vivo pharmacokinetic study.This data that are obtained from formulatation of a nanosystem of ofloxacin (OFLOX) for nose-to-brain delivery to enhance brain accumulation and improve management of bacterial meningitis.
- Dataset
- Data for: Novel gum acacia based macroparticles for colon delivery of Mesalazine: Development and gamma scintigraphy studyData id provided for the Gum Acacia characterization in terms of moisture content, swelling Index and viscosity.
- Dataset
- Data for: Nanostructured lipid carriers containing ondansetron hydrochloride by cold high-pressure homogenization method: preparation, characterization, and pharmacokinetic evaluationThe data describe the preparation, optimization, characterization, and evaluation of nanostructured lipid carriers (NLCs) loaded with ondansetron hydrochloride (OSH), a water-soluble drug. A modified cold high-pressure homogenization method was used, and the pH-dependent solubility of OSH was exploited to obtain NLCs with the enhanced entrapment efficiency (EE). The optimized formulation exhibited the sustained-release characteristic of the drug in vitro. After single subcutaneous injection in rats, the optimized OSH-loaded NLCs could prolong the drug release until 96 h with an extended mean resident time and enhanced systemic exposure compared to the OSH solution.
- Dataset
- Data for: Plasmid BMP-2–Embedded Gelatin Sponge As A Gene-Activated Matrix for Preosteoblast DifferentiationSupplementary Figure 1 To allow endocytosis of DNA complexes into the cells, 5 × 104 cells and TransIT-2020/pEGFP-C1 complexes were mixed for 5, 15, 30, or 60 min (n = 3). Flow cytometry analysis was performed to evaluate GFP expression at these time points using FACS Calibur flow cytometer (Becton Dickinson, Heidelberg, Germany). Cells were gated at 1 × 104 cells/sample in FL1 channel setting, and BMP-2 transfection samples under the same condition at each time point were used as controls(Figure S1A). Transfection efficiencies of these four mixing time points were compared using Becton Dickinson Cell Quest software(Figure S1B). We found that duration of 30 min was the optimal mixing time, as the average GFP expression (9.92%) at 30 min was the highest compared to that at the other three time points. Live and dead assay : The scaffolds were stained using a Live/Dead Cytotoxicity/Viability kit (Invitrogen, Carlsbad, CA)from day 7 to day 28 .The live cells ,dead cells and merge images were all included. Figure 5 ALP supplementary data : all ALP activity corresponding to Figure 5 Figure 6 ARS supplementary data : all ARS activity corresponding to Figure 6 Figure 7 BMP-2 supplementary data: all BMP-2 expression corresponding to Figure 7
- Dataset
- CSD 2095684: Experimental Crystal Structure DeterminationRelated Article: Elizaura H.C. Silva, Elaine S.M. Cutrim, Monica R.C. Iemma, Hernane S. Barud, Alex Rojas, Luis Gómez-Hortigüela, Alan S.de Menezes, Enrique Rodríguez-Castellón, Auro A. Tanaka, Ana C.S. Alcântara|2023|Journal of Drug Delivery Science and Technology|81|104294|doi:10.1016/j.jddst.2023.104294
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- CCDC 2157365: Experimental Crystal Structure DeterminationRelated Article: Jiuyi Sun|2022|CSD Communication|||
- Dataset
- CCDC 2177045: Experimental Crystal Structure DeterminationRelated Article: Duanxiu Li, Jiong Li, Zongwu Deng, Hailu Zhang|2022|Journal of Drug Delivery Science and Technology|78|103934|doi:10.1016/j.jddst.2022.103934
- Dataset
- CCDC 2157366: Experimental Crystal Structure DeterminationRelated Article: Jiuyi Sun|2022|CSD Communication|||
- Dataset
- CCDC 2177046: Experimental Crystal Structure DeterminationRelated Article: Duanxiu Li, Jiong Li, Zongwu Deng, Hailu Zhang|2022|Journal of Drug Delivery Science and Technology|78|103934|doi:10.1016/j.jddst.2022.103934
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