Brain Stimulation

These scripts create and analyze synthetic LFP used in the publication. Scripts are ordered by figures where the data appear. Version 2: Replaced incorrect Fig6 code with the code used to generate the figure in the published figure.

Direct TMS over the left BA9 is associated with significant increases in BOLD signal in adjacent BA46 in schizophrenia patients. Conversely, healthy controls show more effective transcallosal activation

The full set of TMS coil sound recordings and the corresponding TMS-induced electric field recordings for seven figure-8 TMS coils from three manufacturers. In addition, the technical drawings for the probe used for the electric field recordings, to allow reproduction of the measurements.

This data file provides mean accuracy results for each participant. Data are arranged according to TMS Session and TMS stimulation targets.

All raw results data from the trial, provided to allow full transparency in inter-individual variation in outcome measures.

Data used in the figure.

We measured the time courses of interhemispheric facilitation and inhibition with a conditioning-test paired-pulse magnetic stimulation paradigm in 12 subjects. There are four spread sheets in the excel file. The first sheet (subject) listed the information about the subjects we tested. The stimulus intensities used in the experiments were also listed. The second sheet (rough) listed the result of a time course tested with interstimulus interval set at 1 ms resolution. The other two sheets (facilitation precise and inhibition precise) showed the results testing interhemispheric facilitation and inhibition with interstimulus intervals set at 0.1 ms resolution.

The supplementary dataset for “Sound comparison of seven TMS coils at matched stimulation strength”, Brain Stimulation, 13(3), 873-880, 2020. The dataset contains sound waveforms of TMS coil click captured at 25 cm and 100 cm from the coil, in Pascals. There are seven coils in this dataset, and for each coil sound has been recorded at 10 stimulator output settings, 10 TMS pulses at each setting. The sampling rate was 192 kHz, and the waveforms were stored in single-precision floating-point format. The sound waveforms are in a MATLAB struct “sound” stored in a file “sound.mat” which is in the file “sound_mat.zip”. For each coil and intensity, the dataset further contains the electric field waveform for an 85 mm spherical phantom, in volts per meter. From these waveforms we have further estimated the stimulation strength in % RMT for an average subject. The electric field recordings and derived stimulation strengths are in a MATLAB struct “stimulation” stored in a file “stimulation.mat” which is in the file “stimulation_mat.zip”. Further, the dataset contains the technical drawings of the electric-field measurement probe for the spherical phantom in a file “probe.zip”. The file contains Gerber files for a two-layer printed-circuit-board probe, an STL file for the 3d-printed probe holder, and an SVG drawing of the laser-cut alignment plate. Our main findings from the data are summarized by the highlights of the article: • Coil click varies by over 20 dB between TMS coils at matched stimulation strength. • Close to a TMS coil, airborne sound pressure level may reach nearly 140 dB(Z). • During rTMS, continuous airborne sound level may exceed 110 dB(A). • Sound level of rTMS may exceed some standard safety limits for both subject and operator. For more information, refer to the article and its supplement.

Data is owned by Mashhad University of Medical Sciences, Deputy of Research. Website: www.mums.ac.ir

Quadripulse transcranial magnetic stimulation (QPS) was applied to the primary motor cortex (M1), the primary somatosensory cortex (S1), and the supramarginal gyrus (SMG) and angular gyrus (AG), with the inter-stimulus interval (ISI) in the trains of pulses set to either 5 ms (QPS-5) or 50 ms (QPS-50). QPS was repeated at 0.2 Hz for 30 minutes. Excitability change in the target site was examined by means of single pulse transcranial magnetic stimulation (TMS). Results of the average motor-evoked potentials (MEP) ratio from the first dorsal interosseus (FDI) are shown for each time-point.